ITCHING in UREMIA or Cronic KIDNEY FAILURE:Natural Cure
Itching, especially at night, harass many people who suffer from kidney failure. Unfortunately it's
difficult or maybe impossible to get out of this condition with traditional treatments, but one can
get rid of it with suitable natural treatments.
Now we will see treatments with natural products for uremic itching, its causes and used therapies.
Itching that occurs in chronic renal failure (uremia) is a very disabling symptom. It affects over 50%
of patients, whether they are treated with extracorporeal or peritoneal dialysis. It greatly affects quality
of sleep. Patients with itchy uremic report that they cannot sleep at night and consequently experience
drowsiness during the day.
Uremic itching, especially when it's untreatable, is a symptom with devastating impact on the psycho-physical
state of patient. It can be followed by lack of strength, state of restlessness up to depression and is
associated with increased risk of death.
Uremic itching is one of the most frequent, frustrating and potentially disabling manifestations of skin
disease in chronic uremic. This disability can be resolved with use of natural remedies for uremic itching.
There is a link between nerve pathways that cause itching and those responsible for pain. In fact, as for
pain, a group of type C fibers responsible for conduction of this stimulus was identified for itching. They
are able to activate medullary neurons which then transmit signal to thalamic area.
Type C nerve fibers are present in the deep layers of epidermis or in the dermo-epidermal junction of
skin, where they interact with mast cells. They influence production of itching by releasing vasoactive
peptides like histamine, IL-2, some proteases and TNF. Natural remedies for uremic itching are possible
and desirable in the exclusive interest of patients.
Therapies usually used initially use polymethylmethacrylate membranes during dialysis. Then, skin
softeners or capsaicin creams are used (which cannot be applied to large surfaces due to irritating effect).
Subsequently, systemic treatments are carried out with use of ultraviolet B rays (with potential carcinogenic
effect on the skin). Not so with natural solutions for itching in kidney failure.
Anticonvulsant drugs like gabapentin can also be used with possible side effects:
1) Neurotoxicity up to coma.
Moreover, results are unsatisfactory if, as already talk, more than half of the patients continue to have
itching, in addition to the heavy side effects.
But, natural cures for uremic itching can be performed due to their effectiveness and absence of side
effects thanks to action of natural products like Calendula Officinalis and Rhodiola rosea which have
an anti-inflammatory, anti free radical and soothing action.
There are also other natural substances (flavoproteins and other coenzymes such as NAD and NADP)
that contribute to the restoration of mast cell metabolism with the rebalancing of the physiological release
of vasoactive peptides, the functionality of the immune system and the consequent disappearance of
itching. Therefore, natural solutions are not only possible but advisable in the exclusive interest of patients.