Migraine and Sleep Disorders: Natural Remedies

Sleep is very important for recovering energy, maintaining mental health and also psychophysical well-being. Sleep disturbances are often

associated with migraines. Below we see how this happens and the natural cures for migraines.


Sleep deprivation is a neurobiological and physiological stressor, that is, it is a stressor that has consequences for the brain, as well as for many body

systems¹. Sleeping allows for the removal of brain metabolic waste products, which are neurotoxic and accumulate in the central nervous system

during wakefulness².


People with migraines have poorer sleep quality and impaired sleep structure than non-migraineurs. This is what emerges from a study conducted

by researchers from the Wolfson Center for Age-Related Diseases, Institute of Psychiatry, Psychology &  Neuroscience in London and

published  by the journal Neurology.


In the study, adults and children with migraines showed less REM sleep, and patients showed less total sleep time and more wakefulness than

controls (non-migraines). But a natural cure for migraines solves this problem.


A published study  in the journal Brain confirms this theory, showing that in humans, a night of sleep deprivation hinders the removal of molecules

that have accumulated in the brain during the day².


The experiment continued one more night, during which all the participants were allowed to sleep. Despite this second night of rest, the impaired

brain cleansing in the sleep deprivation group was not compensated.


Chronic sleep deprivation increases appetite and energy expenditure, increases inflammatory cytokine levels, decreases parasympathetic tone

and increases sympathetic tone, increases blood pressure, increases evening cortisol levels, and raises insulin and blood glucose values.


In addition, several studies have shown that lack of sleep increases the amount of soluble β-amyloid and the risk of formation of β-amyloid plaques

and leads to an increase in tau levels in the interstitial fluid of the hippocampus. Both proteins (tau and beta amyloid) form aggregates typical of

Alzheimer's disease.


Insufficient sleep increases the risk of developing nocturnal gastroesophageal reflux in women, according to a study published in the Journal of

Clinical Sleep Medicine.


Nocturnal gastroesophageal reflux has been defined as the reporting of heartburn or acid reflux after going to bed, occurring sometimes, often, or

very often. And the onset of nocturnal gastroesophageal reflux was twice as common among women with sleep insufficient or short sleep (less than

six hours of sleep per night) than those with sufficient sleep.


Traditional treatments for migraines, i.e. anti-inflammatories and triptans, have significant side effects ranging from stomach inflammation to an

increased risk of pulmonary embolism (anti-inflammatory) or vasoconstriction of the cerebral vessels, which reduces the nutrition of nerve cells

(triptans), should be used rarely and judiciously. Natural remedies for migraines, on the other hand, having no side effects, can be used regularly

and safely, also restoring sleep integrity.


Therefore, a natural cure for migraines is not only possible but a duty for the integrity of the body, allowing long-term treatment, combining the

restoration of the immune system and the rebalancing of an altered body environment. Natural treatment is implemented with the action of

phytotherapeutic substances such as Rhodiola rosea and Vitis vinifera. They have anti-free radical activity, anti-inflammatory, antiplatelet

action, nourishing the blood vessel wall. Together with other natural substances, such as flavoproteins and coenzymes, they contribute effectively and

not harmful to the restoration of metabolism and the rebalancing of the body environment and ultimately to the restoration of normal sleep.



1) Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, O’Donnell J, Christensen DJ, Nicholson C, Iliff JJ, Takano T, Deane R, Nedergaard M. Sleep          drives metabolite clearance from the adult brain. Science. 2013 Oct 18;342(6156):373-7. doi: 10.1126/science.1241224.

2) Per Kristian Eide, Vegard Vinje, Are Hugo Pripp, Kent-Andre Mardal, Geir Ringstad, Sleep deprivation impairs molecular clearance from the human        brain, Brain, Volume 144, Issue 3, March 2021, Pages 863–874,