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BioCephal

BioCephal

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Quick Overview

Useful product for Headache, Migraine, Dysmenorrhea,Trigeminal neuralgia, Menopausal hot flashes

BIOCEPHAL a Natural Product to be Free



Made in Italy

Product Description

 Nature loves Simple Solutions (William of Ockham)

  

The optimal result as regard what is said might not be guaranteed at 100%,

due to own individual genetic variability

 

 BIOCEPHAL is a natural food supplement which has the properties of an herbal product

 

based on Niacinamide , Riboflavin, Rhodiola Rosea, Vitis Vinifera able to counteract

 

some of the mechanisms which are the basis of reactive diseases such as Headache

 

 (Migraine without / with aura, aura without migraine, Hemiplegic migraine, Cluster 

 

 headache, Tension-type Headache, Menstrual headache or catamenial headache),

 

Trigeminal NeuralgiaPost-herpetic neuralgia (herpes zoster),  Intercostal

 

NeuralgiesFibromialgic  neuralgia, Dysmenorrhea and Menopausal Hot

 

Flashes linked to the uncontrolled production of mediators of the nervous transmission.

 


The powerful antioxidant activity of 
Rhodiola Rosea

 

and Vitis vinifera further stabilizes the production of

 

neurotransmitters, fighting free radicals that damage

 

 nervous cells. 

 

The perfectly balanced components of Biocephal have, therefore, a neurotropic

 

action (act by restoring the normal function of the nervous system).

 

 The intake of BIOCEPHAL allows to maintain optimal levels of nutrients needed for

 

the physiological functioning of these complex biochemical systems.

 

Don’t have side effects, does not accumulate in the body, has no interactions

 

with any medication and contraindications. Gluten and lactose free.

 

A product To Be Free

 

 Tested in Headache Center at Hospital St. Charles of Nancy (Dir. Prof.

 

  D.Moscato). Presented at the XXII Congress of Italian Society for the

 

 Study of Headaches (SISC). Published in "J.Headache Pain"

 

 2008-pagg.55-56.

  

European patent no. 1318815 - US patent no. 7,456,291 B2

   

 

Russia patent n. RU 2274448 - China patent n. 01813823.3

 

 

Canada patent n. 2.417.758

 

  

BIOCEPHAL by Green Bios. Packs of 30 capsules. Cost (Euro 13,00).

 

 In Pharmacy, no prescription.  Store below 30° C (86° F)

 

 Made in Italy by R.E.F. - Roma - Via Tor Sapienza,211

 


Headache, Migraine, Trigeminal Neuralgia:

 

 1 capsule after breakfast and lunch three months (twice a day). Subsequently,

 

cps after breakfast and lunch (twice a day) for 15 days every month or 1

 

capsule after breakfast all months.

 

 For a weight exceeding 80 kg. (176 lbs.) or age over 65years it is recommended

 

 to take 3 capsules a day both in initial period and in maintenance.

 

 In cases of intense and prolonged pain it is recommended to double the dose

 

 (2 capsules twice a day until 80 kg.- 176 lbs.- or 2 capsules three times a

 

 day over 80 kg. or 65 years of age) until disappearance of the pain and then

 

to continue with the regular dose.

 

Children under 30 kg: 1 capsule a day for 3 months . Subsequently, 1 cps

 

a day for 15 days each month (the capsules can be opened and poured

 

into water or milk).

 

Children above 30 kg.: dose as the adults.

 

 

Cluster headache: (in case of pain) two capsules after breakfast and

 

lunch (four a day) until the disappearance of pain (10-15 days).

 

For a weight exceeding 80 kg. (176 lbs.) or age over 65 years :

 

two capsules after breakfast, lunch and dinner  ( six capsules a day)

 

until the disappearance of pain.

 

Cluster headache: (prevention of pain) one capsule after breakfast and

 

lunch three months (twice a day). Subsequently, 1 cps. after breakfast

 

and lunch for 15 days every month or 1 capsule a day all months.

 

For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is

 

recommended to take 3 capsules a day .

 


Menopausal hot flashes : 1 capsule after 
breakfast and lunch until the

 

disappearance of the hot flashes. Subsequently, 1 capsule after breakfast. 

 

For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is recommended

 

to take 3 capsules a day.

 

 

Fibromyalgia neuralgies : 1 capsule after breakfast and lunch.

 

For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is

 

recommended to take 3 capsules a day .

 


Post-herpetic neuralgia, Intercostal neuralgies: Adults: 1 capsule

 

after breakfast and lunch until the end of the pain. 

 

In cases of intense and prolonged pain it is recommended to take 2

 

capsules twice a day ( four a day) until the disappearance of the pain.

 

For a weight exceeding 80 kg. (176 lbs.)or age over 65 years : 1 capsule after

 

breakfast, lunch and dinner until the end of the pain or 2 capsules twice a day

 

until the disappearance of the pain.

 

 

In all the previous pathologies, the first positive effects already at the end of the first


month will begin to appear.

 


N.B. Biocephal is not a symptomatic (namely not acting on the pain directly but

 

gradually restores the normal operation and the integrity of the nervous system

 

before damaged and in this way it removes the pain), therefore during the first

 

period of care, to counteract the pain’s crisis of headache you can use the usual

 

drugs, as needed.


If the pain is intense, begin with three capsules a day (morning, noon and

 

evening) for 7-10 days and then continue with two capsules a day.

 

 


BIOCEPHAL can also counteract some biochemical mechanisms that

 

underlie other diseases reactive as dysmenorrhea (pain and menstrual

 

irregularities), menopausal flashes because the mechanism of these is the

 

same of headaches, but varies the seat: indeed, in the headaches the

 

cause is a contraction of the meningeal arteries, in dysmenorrhea or

 

menopausal problems the contraction is on the uterine artery.


Dosage : 1 capsule after main meals for 4 months (twice a day).

 

Subsequently, 1 cps after main meals for 15 days each month from ten

 

days before the date of the menstruation (twice a day). After 4-5 months

 

of therapy the intervals of menstruation will become regular too.

 

NB In the crisis particularly intense and prolonged for the first 3 months is

 

recommended to take 3 capsules daily. For a weight exceeding 80 kg. (176

 

lbs) it is recommended to take 3 capsules a day both in initial period

 

and in maintenance.

 

 


To purchase our products online ( too for Europe and USA )

Follow the links below:
 



1)
http://www.omeosalute.it/lista.php?q=biocephal 

 


2) 
http://www.omeosalute.it/spese_spedizione.php

 


Contacts online pharmacy tel. 0444.544017 / e-mail:

 

info@naturalgenerics.it

 

 

also (Italy and Europe) 

 

 

1- https://www.farmaspeed.it/itm/biocephal-30-capsule/4722

 

 

2- www.farmaspeed.it/contenuti/spedizioni.asp

 

 

 


MECHANISM OF MIGRAINE AND DYSMENORRHOEA

 

 
The reason of the migraine’s pain is a neurogenic steril inflammation of the

 

trigeminovascular vessels, due to degranulation of mastcells.

 

The stimulation of trigeminal innervation in the brain dura mater cause

 

pain due to nervous fibers activation of cerebral blood vessels.

 

During a migraine attack there is an overflow of plasmatic proteins and the

 

development of localized inflammation of intracranial blood vessels. This

 

phenomenon is triggered by an incorrect degranulation of mastcells and

 

consequently an activation of trigeminal innervation of cerebral blood

 

vessels. This event cause a caotic release of certain peptidic

 

neurotransmitters wich have a vasodilatatory effect and are contained in

 

the nerve fibres of the trigeminovascular system, in particular CGRP

 

(calcitonin gene-related peptide), leucotriens, neurokinines, istamin,

 

prostaglandines .

 

The same neurogenic steril inflammation happens into blood vessels of

 

uterine artery and too here is triggered by mastcells degranulation. This

 

inflammation cause a caotic release of peptidic neurotransmitters into

 

blood vessels of uterin artery which have a vasodilatatory effect

 

(neurokinines, istamin, prostaglandins.. .). Such event cause too disorders

 

on the frequency of regularity of the menstruation.

 

Niacin and riboflavin play a crucial role in the metabolism of mastocytes

 

(mastcells). A deficiency of either of these agents will adversely affect the

 

energy production phase of the metabolic chain that leads to the activation

 

of these cells, that is mainly responsible for releasing the biochemical

 

mediators and neurotransmitters mentioned above, which are the origin

 

both of migraine, trigeminal neuralgia, pain and menstrual irregularities

 

and other reactive pathologies (Menopausal hot flashes).

 

The powerful antioxidant activity of Rhodiola Rosea and Vitis vinifera

 

stabilizes further on, the production of neuro-transmitters, counteracting

 

free radicals that damage brain and nervous cells, regularizing the

 

microcirculation and balancing the mood.


 Nature loves Simple Solutions (William of Ockham)

 


Bibliography:


1)Curr.Opin. Neurology 2004 Jun;17(3):289-93. Migraine aura:new

    information on underlying mechanisms.Sanchez-del Rio M,Reuter U. 

 

2)Child Psychiatry Hum.Dev. 2001 Fall;32(1):45-54. Serotonin mediated

    cluster headache,trigeminal neuralgia,and superiorlaryngeal neuralgia

    with SAD chronicity. Weiss JL, Weiss KL, Benecke SM. 

 

3)Clin Exp Immunol 2003 Gen;131(1):48-52. Nicotinamide e’ un potente

   inibitore delle citochine proinfiammatorie. Ungerstedt JS, Blömback M, T

   Söderström.


4)Gli acidi nucleici J.2010 Lug.25;Pll:Ruolo della nicotinamide nel danno al

   DNA, mutagenesi e riparazione del DNA. Suriana D, GM Halliday, Damian

   DL.  

 

5)J. Investig Dermatol Symp Proc. 2006 Sep;126(9):2074-86.Epub 2006

   May 11.Serine protease signaling of epidermal permeability barrier

   homeostasis,Hachem JP,Houben E,Crumrine D,Man MQ,Schurer

   N,Roelandt T,Choi EH,Uchida Y,Brown BE,Feingold KR,Elias PM.
 

6) J. Steroid Biochem Mol. Biol. 2014 Jul;142:115-20. doi:

   10.1016/j.jsbmb.2013.08.010. Epub 2013 Sep 4.

   Menopausal hot flashes: mechanisms, endocrinology, treatment.

   Freedman RR