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Useful product for Headache, Migraine, Dysmenorrhea,Trigeminal neuralgia, Menopausal hot flashes

BIOCEPHAL a Natural Product to be Free

Made in Italy

Product Description

 Nature loves Simple Solutions (William of Ockham)


The optimal result as regard what is said might not be guaranteed at 100%,

due to own individual genetic variability


 BIOCEPHAL is a natural food supplement which has the properties of an herbal product


based on Niacinamide , Riboflavin, Rhodiola Rosea, Vitis Vinifera able to counteract


some of the mechanisms which are the basis of reactive diseases such as Headache


 (Migraine without / with aura, aura without migraine, Hemiplegic migraine, Cluster 


 headache, Tension-type Headache, Menstrual headache or catamenial headache),


Trigeminal NeuralgiaPost-herpetic neuralgia (herpes zoster),  Intercostal


NeuralgiesFibromialgic  neuralgia, Dysmenorrhea and Menopausal Hot


Flashes linked to the uncontrolled production of mediators of the nervous transmission.


The powerful antioxidant activity of 
Rhodiola Rosea


and Vitis vinifera further stabilizes the production of


neurotransmitters, fighting free radicals that damage


 nervous cells. 


The perfectly balanced components of Biocephal have, therefore, a neurotropic


action (act by restoring the normal function of the nervous system).


 The intake of BIOCEPHAL allows to maintain optimal levels of nutrients needed for


the physiological functioning of these complex biochemical systems.


Don’t have side effects, does not accumulate in the body, has no interactions


with any medication and contraindications. Gluten and lactose free.


A product To Be Free


 Tested in Headache Center at Hospital St. Charles of Nancy (Dir. Prof.


  D.Moscato). Presented at the XXII Congress of Italian Society for the


 Study of Headaches (SISC). Published in "J.Headache Pain"




European patent no. 1318815 - US patent no. 7,456,291 B2



Russia patent n. RU 2274448 - China patent n. 01813823.3



Canada patent n. 2.417.758



BIOCEPHAL by Green Bios. Packs of 30 capsules. Cost (Euro 13,00).


 In Pharmacy, no prescription.  Store below 30° C (86° F)


 Made in Italy by R.E.F. - Roma - Via Tor Sapienza,211


Headache, Migraine, Trigeminal Neuralgia:


 1 capsule after breakfast and lunch three months (twice a day). Subsequently,


cps after breakfast and lunch (twice a day) for 15 days every month or 1


capsule after breakfast throughout the month.


 For a weight exceeding 80 kg. (176 lbs.) or age over 65years it is recommended


 to take 3 capsules a day both in initial period and 2 caps. in maintenance.


 In cases of intense and prolonged pain it is recommended to double the dose


 (2 capsules twice a day until 80 kg.- 176 lbs.- or 2 capsules three times a


 day over 80 kg. or 65 years of age) until disappearance of the pain and then


to continue with the regular dose.


Children under 30 kg: 1 capsule a day for 3 months . Subsequently, 1 cps


a day for 15 days each month (the capsules can be opened and poured


into water or milk).


Children above 30 kg.: dose as the adults.



Cluster headache: (in case of pain) two capsules after breakfast and


lunch (four a day) until the disappearance of pain (10-15 days).


For a weight exceeding 80 kg. (176 lbs.) or age over 65 years :


two capsules after breakfast, lunch and dinner  ( six capsules a day)


until the disappearance of pain.


Cluster headache: ( pain prevention) one capsule after breakfast and


lunch three months (twice a day). Subsequently, 1 cps. after breakfast


and lunch for 15 days every month or 1 capsule a day throughout the month.


For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is


recommended to take 3 capsules a day (1 after breakfast and 2 after lunch).


Menopausal hot flashes : 1 capsule after 
breakfast and lunch until the


disappearance of the hot flashes. Subsequently, 1 capsule after breakfast. 


For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is recommended


to take 3 capsules a day (1 after breakfast and 2 after lunch).



Fibromyalgia neuralgies : 1 capsule after breakfast and lunch.


For a weight exceeding 80 kg. (176 lbs.) or age over 65 years it is


recommended to take 3 capsules a day .


Post-herpetic neuralgia, Intercostal neuralgies: Adults: 1 capsule


after breakfast and lunch until the end of the pain. 


In cases of intense and prolonged pain it is recommended to take 2


capsules twice a day ( four a day) until the disappearance of the pain.


For a weight exceeding 80 kg. (176 lbs.)or age over 65 years : 1 capsule after


breakfast, lunch and dinner until the end of the pain or 2 capsules twice a day


until the disappearance of the pain.



In all the previous pathologies, the first positive effects already at the end of the first

month will begin to appear.


N.B. Biocephal is not a symptomatic (namely not acting on the pain directly but


gradually restores the normal operation and the integrity of the nervous system


before damaged and in this way it removes the pain), therefore during the first


period of care, to counteract the pain’s crisis of headache you can use the usual


drugs, as needed.

If the pain is intense, begin with three capsules a day (morning, noon and


evening) for 7-10 days and then continue with two capsules a day.



BIOCEPHAL can also counteract some biochemical mechanisms that


underlie other diseases reactive as dysmenorrhea (pain and menstrual


irregularities), menopausal flashes because the mechanism of these is the


same of headaches, but varies the seat: indeed, in the headaches the


cause is a contraction of the meningeal arteries, in dysmenorrhea or


menopausal problems the contraction is on the uterine artery.

Dosage : 1 capsule after main meals for 4 months (twice a day).


Subsequently, 1 cps after main meals for 15 days each month from ten


days before the date of the menstruation (twice a day). After 4-5 months


of therapy the intervals of menstruation will become regular too.


NB In the crisis particularly intense and prolonged for the first 3 months is


recommended to take 3 capsules daily. For a weight exceeding 80 kg. (176


lbs) it is recommended to take 3 capsules a day both in initial period


and in maintenance.



To purchase our products online ( too for Europe and USA )

Follow the links below:





Contacts online pharmacy tel. 0444.544017 / e-mail:





also (Italy and Europe) 



1- https://www.farmaspeed.it/itm/biocephal-30-capsule/4722



2- www.farmaspeed.it/contenuti/spedizioni.asp






The reason of the migraine’s pain is a neurogenic steril inflammation of the


trigeminovascular vessels, due to degranulation of mastcells.


The stimulation of trigeminal innervation in the brain dura mater cause


pain due to nervous fibers activation of cerebral blood vessels.


During a migraine attack there is an overflow of plasmatic proteins and the


development of localized inflammation of intracranial blood vessels. This


phenomenon is triggered by an incorrect degranulation of mastcells and


consequently an activation of trigeminal innervation of cerebral blood


vessels. This event cause a caotic release of certain peptidic


neurotransmitters wich have a vasodilatatory effect and are contained in


the nerve fibres of the trigeminovascular system, in particular CGRP


(calcitonin gene-related peptide), leucotriens, neurokinines, istamin,


prostaglandines .


The same neurogenic steril inflammation happens into blood vessels of


uterine artery and too here is triggered by mastcells degranulation. This


inflammation cause a caotic release of peptidic neurotransmitters into


blood vessels of uterin artery which have a vasodilatatory effect


(neurokinines, istamin, prostaglandins.. .). Such event cause too disorders


on the frequency of regularity of the menstruation.


Niacin and riboflavin play a crucial role in the metabolism of mastocytes


(mastcells). A deficiency of either of these agents will adversely affect the


energy production phase of the metabolic chain that leads to the activation


of these cells, that is mainly responsible for releasing the biochemical


mediators and neurotransmitters mentioned above, which are the origin


both of migraine, trigeminal neuralgia, pain and menstrual irregularities


and other reactive pathologies (Menopausal hot flashes).


The powerful antioxidant activity of Rhodiola Rosea and Vitis vinifera


stabilizes further on, the production of neuro-transmitters, counteracting


free radicals that damage brain and nervous cells, regularizing the


microcirculation and balancing the mood.

 Nature loves Simple Solutions (William of Ockham)



1)Curr.Opin. Neurology 2004 Jun;17(3):289-93. Migraine aura:new

    information on underlying mechanisms.Sanchez-del Rio M,Reuter U. 


2)Child Psychiatry Hum.Dev. 2001 Fall;32(1):45-54. Serotonin mediated

    cluster headache,trigeminal neuralgia,and superiorlaryngeal neuralgia

    with SAD chronicity. Weiss JL, Weiss KL, Benecke SM. 


3)Clin Exp Immunol 2003 Gen;131(1):48-52. Nicotinamide e’ un potente

   inibitore delle citochine proinfiammatorie. Ungerstedt JS, Blömback M, T


4)Gli acidi nucleici J.2010 Lug.25;Pll:Ruolo della nicotinamide nel danno al

   DNA, mutagenesi e riparazione del DNA. Suriana D, GM Halliday, Damian



5)J. Investig Dermatol Symp Proc. 2006 Sep;126(9):2074-86.Epub 2006

   May 11.Serine protease signaling of epidermal permeability barrier

   homeostasis,Hachem JP,Houben E,Crumrine D,Man MQ,Schurer

   N,Roelandt T,Choi EH,Uchida Y,Brown BE,Feingold KR,Elias PM.

6) J. Steroid Biochem Mol. Biol. 2014 Jul;142:115-20. doi:

   10.1016/j.jsbmb.2013.08.010. Epub 2013 Sep 4.

   Menopausal hot flashes: mechanisms, endocrinology, treatment.

   Freedman RR